SENP1-IN-4, a distinct inhibitor of the deSUMOylation protease 1 (SENP1), is designed to enhance tumor radiosensitivity.

SENP1-IN-4 improves the sensitivity of tumor cells to irradiation[1]. SENP1-IN-4 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC 50 of >20 μM[1]. Cell Cytotoxicity Assay[1]Cell Line: Hela cells Concentration: 0.7 μ M, 2.2 μM, 6.6 μM、20 μM Incubation Time: 72 hours Result: IC 50 >20 μM