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Anti-MICA Antibody (3K607)

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产品编号 TMAY-02316
别名 PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2

Anti-MICA Antibody (3K607) 是一种 Mouse 抗体,靶向 MICA。Anti-MICA Antibody (3K607) 可用于 ELISA,FCM。

Anti-MICA Antibody (3K607)

Anti-MICA Antibody (3K607)

Rating icon 还可以
产品编号 TMAY-02316 别名 PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2

Anti-MICA Antibody (3K607) 是一种 Mouse 抗体,靶向 MICA。Anti-MICA Antibody (3K607) 可用于 ELISA,FCM。

规格价格库存数量
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-MICA Antibody (3K607) is a Mouse antibody targeting MICA. Anti-MICA Antibody (3K607) can be used in ELISA,FCM.
别名PERB11.1, MIC-A, MHC class I polypeptide-related sequence A, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
Ig Type
Monoclonal Mouse IgG1
克隆号
3K607
交叉反应
Human
验证活性
Flow cytometric analysis of Human MICA expression on HeLa cells. Cells were stained with purified anti-Human MICA, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
ELISA,FCM
推荐剂量
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICA (rh MICA; TMPY-02053; AAH16929.1; Met1-Gln308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human MICA Protein (TMPY-02053)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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