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Anti-Claudin 2 Antibody (3U888)

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货号 TMAB-04424

Anti-Claudin 2 Antibody (3U888) 是一种 Mouse 抗体，靶向 Claudin 2。Anti-Claudin 2 Antibody (3U888) 可用于 IHC-P,IHC-Fr,IF。

Anti-Claudin 2 Antibody (3U888)

Anti-Claudin 2 Antibody (3U888)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04424

Anti-Claudin 2 Antibody (3U888) 是一种 Mouse 抗体，靶向 Claudin 2。Anti-Claudin 2 Antibody (3U888) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
200 μg
¥ 5,590
5日内发货
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Claudin 2 Antibody (3U888) is a Mouse antibody targeting Claudin 2. Anti-Claudin 2 Antibody (3U888) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3U888
反应种属
Human (predicted:Mouse,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cell junction; tight junction. Cell membrane.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. The gene encoding claudin-2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin 2
抗原种属
Human
基因名称
CLDN2
基因ID
9075
蛋白名称
Claudin-2
Uniprot ID
P57739
功能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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