- 全部删除
- 您的购物车当前为空
(Rac)-Roscovitine ((Rac)-Seliciclib) 是一种选择性抑制周期蛋白依赖性激酶 (CDKs) 的化合物,通过与 ATP 竞争性结合 CDKs 的活性位点来阻止其磷酸化活性,从而诱导癌细胞凋亡 (apoptosis)。该化合物有潜力用于研究与CDK失调相关的多种疾病,包括癌症、神经退行性疾病、心脏疾病、病毒和原虫感染、肾小球肾炎以及慢性炎症。
(Rac)-Roscovitine ((Rac)-Seliciclib) 是一种选择性抑制周期蛋白依赖性激酶 (CDKs) 的化合物,通过与 ATP 竞争性结合 CDKs 的活性位点来阻止其磷酸化活性,从而诱导癌细胞凋亡 (apoptosis)。该化合物有潜力用于研究与CDK失调相关的多种疾病,包括癌症、神经退行性疾病、心脏疾病、病毒和原虫感染、肾小球肾炎以及慢性炎症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 待询 | 10-14周 | |
50 mg | 待询 | 10-14周 |
(Rac)-Roscovitine 相关产品
产品描述 | (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs). It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation. |
别名 | (Rac)-Seliciclib, (Rac)-CYC202 |
分子量 | 354.449 |
分子式 | C19H26N6O |
CAS No. | 186692-44-4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
评论内容