MAPRE3 (Microtubule Associated Protein RP/EB Family Member 3, also known as EB3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. MAPRE3 is a member of the RP/EB family. It localizes to the cytoplasmic microtubule network and binds APCL. MAPRE3 regulates the dynamics of the microtubule cytoskeleton and promotes microtubule growth. It may be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. MAPRE3 may also play a role in cell migration. MAPRE3 is broadly expressed in the brain, testis, and other tissues. Diseases associated with MAPRE3 include Neuronopathy, Distal Hereditary Motor, Type Viib, and Distal Hereditary Motor Neuronopathy Type 7.
生物活性 | Testing in progress |
产品描述 | MAPRE3 (Microtubule Associated Protein RP/EB Family Member 3, also known as EB3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. MAPRE3 is a member of the RP/EB family. It localizes to the cytoplasmic microtubule network and binds APCL. MAPRE3 regulates the dynamics of the microtubule cytoskeleton and promotes microtubule growth. It may be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. MAPRE3 may also play a role in cell migration. MAPRE3 is broadly expressed in the brain, testis, and other tissues. Diseases associated with MAPRE3 include Neuronopathy, Distal Hereditary Motor, Type Viib, and Distal Hereditary Motor Neuronopathy Type 7. |
种属 | Human |
表达系统 | E. coli |
标签 | N-His |
蛋白编号 | Q9UPY8-1 |
别名 | microtubule-associated protein, RP/EB family, member 3, EB3, RP3, EBF3, EBF3-S |
蛋白构建 | Human MAPRE3 (Q9UPY8-1) (Met1-Tyr281) |
蛋白纯度 | > 95 % as determined by SDS-PAGE |
分子量 | 33.8 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 10% glycerol, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | MAPRE3 (Microtubule Associated Protein RP/EB Family Member 3, also known as EB3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. MAPRE3 is a member of the RP/EB family. It localizes to the cytoplasmic microtubule network and binds APCL. MAPRE3 regulates the dynamics of the microtubule cytoskeleton and promotes microtubule growth. It may be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. MAPRE3 may also play a role in cell migration. MAPRE3 is broadly expressed in the brain, testis, and other tissues. Diseases associated with MAPRE3 include Neuronopathy, Distal Hereditary Motor, Type Viib, and Distal Hereditary Motor Neuronopathy Type 7. |
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EB3 Protein, Human, Recombinant (His) microtubule-associated protein, RP/EB family, member 3 RP 3 RP-3 EB3 EB-3 RP3 EBF3 EBF-3 EBF 3 EB 3 EBF3-S recombinant recombinant-proteins proteins protein