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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CTNND2/delta 2 Catenin Polyclonal Antibody

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货号 TMAB-04764

Anti-CTNND2/delta 2 Catenin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CTNND2/delta 2 Catenin。Anti-CTNND2/delta 2 Catenin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CTNND2/delta 2 Catenin Polyclonal Antibody

Anti-CTNND2/delta 2 Catenin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04764

Anti-CTNND2/delta 2 Catenin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CTNND2/delta 2 Catenin。Anti-CTNND2/delta 2 Catenin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CTNND2/delta 2 Catenin Polyclonal Antibody is a Rabbit antibody targeting CTNND2/delta 2 Catenin. Anti-CTNND2/delta 2 Catenin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Predominantly expressed in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CTNND2/delta 2 Catenin
抗原种属
Human
基因名称
CTNND2
基因ID
1501
蛋白名称
Catenin delta-2
Uniprot ID
Q9UQB3
功能
Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
化学信息
分子量Theoretical: 133 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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