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Anti-CXADR/CAR Antibody-PE (7D440)
还可以产品编号 TMAY-01175P
Anti-CXADR/CAR Antibody-PE (7D440) 是一种 PE-conjugated Rabbit 抗体，靶向 CXADR/CAR。Anti-CXADR/CAR Antibody-PE (7D440) 可用于 FCM。
Anti-CXADR/CAR Antibody-PE (7D440)
Anti-CXADR/CAR Antibody-PE (7D440)
还可以产品编号 TMAY-01175P
Anti-CXADR/CAR Antibody-PE (7D440) 是一种 PE-conjugated Rabbit 抗体，靶向 CXADR/CAR。Anti-CXADR/CAR Antibody-PE (7D440) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CXADR/CAR Antibody-PE (7D440) is a PE-conjugated Rabbit antibody targeting CXADR/CAR. Anti-CXADR/CAR Antibody-PE (7D440) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7D440 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human CXADR expression on HT-29 cells. HT-29 cells were stained with PE-conjugated anti-Human CXARD. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CXADR / CAR (rh CXADR / CAR; TMPY-02121; NP_001329.1; Met1-Gly237) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/FITC |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human CXADR / CAR protein (TMPY-02121) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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