规格

价格

库存

数量

2 mg

¥ 789

5日内发货

5 mg

¥ 1,330

5日内发货

25 mg

¥ 5,300

6-8周

50 mg

¥ 6,890

6-8周

100 mg

¥ 11,200

6-8周

1 mL x 10 mM (in DMSO)

¥ 1,460

5日内发货

生物活性

产品描述	L-690330 is a competitive inositol monophosphatase inhibitor (Kis: 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase). L-690330 shows 10-fold more sensitive than a mouse and rat IMPase.
靶点活性	IMPase (bovine recombinant):0.19 μM(ki), IMPase (bovine frontal cortex):0.42 μM, IMPase (human recombinant):(ki)0.27 μM, IMPase (human frontal cortex):0.30 μM(ki)
体外活性	In HEK293 cells, L-690330 (50 μM; 1 hour) causes P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression[2].
体内活性	Except for a reduction in time spent in light in the dark/light test, L-690330 (intracerebroventricular?injection; 0.1 μmol) shows no effects on their motor activity and coordination in the beam walking [3].

化学信息

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 33.33 mg/mL (111.8 mM), Sonication is recommended.

DMSO: 25 mg/mL (83.86 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (6.71 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO/H2O