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Anti-TLR3 Antibody (4T47)

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Anti-TLR3 Antibody (4T47)
产品编号 TMAY-03149
别名 toll like receptor 3, IIAE2, CD283

Anti-TLR3 Antibody (4T47) 是一种 Rabbit 抗体,靶向 TLR3。Anti-TLR3 Antibody (4T47) 可用于 ELISA。

Anti-TLR3 Antibody (4T47)

Anti-TLR3 Antibody (4T47)

Rating icon 还可以
Anti-TLR3 Antibody (4T47)
产品编号 TMAY-03149 别名 toll like receptor 3, IIAE2, CD283

Anti-TLR3 Antibody (4T47) 是一种 Rabbit 抗体,靶向 TLR3。Anti-TLR3 Antibody (4T47) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

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产品描述
Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
别名toll like receptor 3, IIAE2, CD283
Ig Type
Rabbit IgG
克隆号
4T47
交叉反应
Mouse
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TLR3 / CD283 (TMPY-01396; NP_569054.2; Met1-Leu705).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3/CD283 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA, a sign of viral infection. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse TLR3 / CD283 protein (TMPY-01396)
抗原种属
Mouse
研究领域
Neuroinflammation, Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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