Anti-TLR3 Antibody (4T47)

Name: Anti-TLR3 Antibody (4T47)
Brand: TargetMol
SKU: TMAY-03149
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03149

Anti-TLR3 Antibody (4T47) 是一种 Rabbit 抗体，靶向 TLR3。Anti-TLR3 Antibody (4T47) 可用于 ELISA。

Anti-TLR3 Antibody (4T47)

还可以

产品编号 TMAY-03149

Anti-TLR3 Antibody (4T47) 是一种 Rabbit 抗体，靶向 TLR3。Anti-TLR3 Antibody (4T47) 可用于 ELISA。

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产品描述	Anti-TLR3 Antibody (4T47) is a Rabbit antibody targeting TLR3. Anti-TLR3 Antibody (4T47) can be used in ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	4T47
交叉反应	Mouse
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TLR3 / CD283 (TMPY-01396; NP_569054.2; Met1-Leu705).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a member of the Toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3/CD283 plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA, a sign of viral infection. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse TLR3 / CD283 protein (TMPY-01396)
抗原种属	Mouse
研究领域	Neuroinflammation, Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.