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Anti-UBE2D1 Antibody (3N219)
还可以产品编号 TMAY-01865
Anti-UBE2D1 Antibody (3N219) 是一种 Mouse 抗体，靶向 UBE2D1。Anti-UBE2D1 Antibody (3N219) 可用于 FCM。
Anti-UBE2D1 Antibody (3N219)
Anti-UBE2D1 Antibody (3N219)
还可以产品编号 TMAY-01865
Anti-UBE2D1 Antibody (3N219) 是一种 Mouse 抗体，靶向 UBE2D1。Anti-UBE2D1 Antibody (3N219) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-UBE2D1 Antibody (3N219) is a Mouse antibody targeting UBE2D1. Anti-UBE2D1 Antibody (3N219) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 3N219 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human UBE2D1 expression on A431 cells. Cells were stained with purified anti-Human UBE2D1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human UBE2D1 Protein (TMPY-02426) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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