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顶部生物活性储存和溶解信息计算器

Anti-OSMR Antibody (7J924)

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Anti-OSMR Antibody (7J924)
产品编号 TMAY-01776
别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody (7J924) 是一种 Rabbit 抗体，靶向 OSMR。Anti-OSMR Antibody (7J924) 可用于 ELISA。

Anti-OSMR Antibody (7J924)
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Anti-OSMR Antibody (7J924)

Rating icon 还可以
Anti-OSMR Antibody (7J924)
产品编号 TMAY-01776 别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody (7J924) 是一种 Rabbit 抗体，靶向 OSMR。Anti-OSMR Antibody (7J924) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-OSMR Antibody (7J924) is a Rabbit antibody targeting OSMR. Anti-OSMR Antibody (7J924) can be used in ELISA.
别名OSMRB, oncostatin M receptor
Ig Type
Rabbit IgG
克隆号
7J924
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR / IL-31RB (rh OSMR / IL-31RB; TMPY-01305; NP_003990.1; Met 1-Met 740).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human OSMR / IL-31RB Protein (TMPY-01305)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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