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Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CREM (Ser271+Ser274)。Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CREM (Ser271+Ser274)。Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CREM (Ser271+Ser274). Anti-Phospho-CREM (Ser271+Ser274) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Chicken,Pig,Horse) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in testes (round spermatids) (at protein level). Isoform 14 is the major activator form in testes. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | CREM is a a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is derived from a multiexonic gene that encodes both activators and antagonists of cAMP-inducible transcription by differential splicing. Splice variants with antagonistic function lack 2 glutamine-rich domains and block cAMP-induced transcription, whereas an isoform that includes these glutamine-rich domains is a transcriptional activator. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human CREM around the phosphorylation site of Ser271 + Ser274 |
| 抗原种属 | Human |
| 基因名称 | CREM |
| 基因ID | |
| 蛋白名称 | cAMP-responsive element modulator |
| Uniprot ID | |
| 功能 | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation. |
| 分子量 | Theoretical: 37 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |