Name: VEGFD Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-02589
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 388

6-8日内发货

10 μg

¥ 629

6-8日内发货

20 μg

¥ 987

5日内发货

50 μg

¥ 1,980

5日内发货

100 μg

¥ 3,970

5日内发货

生物活性

产品描述	VEGFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is P97946.
生物活性	1. Measured by its binding ability in a functional ELISA. 2. Immobilized human VEGFR3-His at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The EC50 of mouse Fc-VEGFD is 49 ng/mL. 3. Immobilized mouse VEGFR3-His at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The EC50 of mouse Fc-VEGFD is 44 ng/mL.
研究背景	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.
种属	Mouse
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	P97946
蛋白构建	A DNA sequence encoding the mature form of mouse FIGF (P97946) (Phe 98-Ser 206) was fused with the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	VEGF-D, Vegfd, c-fos induced growth factor (vascular endothelial growth factor D), AI325264
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	40.6 kDa (predicted); 45 and 36 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

VEGFD Protein, Mouse, Recombinant (hFc)

VEGFD Protein, Mouse, Recombinant (hFc)

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