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Anti-CDX1 Antibody (5H993)

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Anti-CDX1 Antibody (5H993)
产品编号 TMAC-00806
别名 Homeobox protein CDX-1, CDX 1, Caudal-type homeobox protein 1

Anti-CDX1 Antibody (5H993) 是一种 Rabbit 抗体,靶向 CDX1。Anti-CDX1 Antibody (5H993) 可用于 WB,ICC。

Anti-CDX1 Antibody (5H993)

Anti-CDX1 Antibody (5H993)

Rating icon 还可以
Anti-CDX1 Antibody (5H993)
产品编号 TMAC-00806 别名 Homeobox protein CDX-1, CDX 1, Caudal-type homeobox protein 1

Anti-CDX1 Antibody (5H993) 是一种 Rabbit 抗体,靶向 CDX1。Anti-CDX1 Antibody (5H993) 可用于 WB,ICC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDX1 Antibody (5H993) is a Rabbit antibody targeting CDX1. Anti-CDX1 Antibody (5H993) can be used in WB,ICC.
别名Homeobox protein CDX-1, CDX 1, Caudal-type homeobox protein 1
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Cdx1 on human small intestine tissue (1) and CRC cell (2) lysate using anti-Cdx1 antibody at 1/1,000 dilution.
2. ICC staining Cdx1 in HOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:500-2000; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The members of the murine Cdx family (Cdx1, Cdx2, and Cdx4) are members of the caudal-type homeobox family of genes, which are homologues of the Drosophila 'caudal' gene required for anterior-posterior regional identity. The intestine-specific transcription factors Cdx1 and Cdx2 are candidate genes for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. The relative expression of Cdx1 to Cdx2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Expression of the Cdx1 homeobox gene in epithelial intestinal cells promotes cellular growth and differentiation. Cdx1 positively regulates its own expression. Cdx1 and Cdx2 are expressed in the small intestine and colon of fetus and adult. A decrease in human Cdx1 and/or Cdx2 expression is associated with colorectal tumorigenesis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways. The human Cdx1 gene maps to chromosome 5q31-q33 and encodes a 265-amino acid protein.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: full lenth sequence of human Cdx1
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 28 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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