Name: MB-311
Brand: TargetMol
SKU: T9901A-1267
Rating: 4.5 (1 reviews)

生物活性

产品描述	MB-311 is a fully humanized monoclonal antibody targeting the tumor-associated antigen Lewis Y (LeY), acting by specifically binding to the LeY carbohydrate structures on the surface of tumor cells. The compound is an essential tool for investigating immunotherapy mechanisms against carbohydrate antigens, aiming to achieve precise clearance of tumor cells by inducing robust antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
体外活性	在表达人 Lewis Y 的肿瘤细胞系中，MB-311 诱导了强效的 ADCC 并刺激了 TNF-alpha 和 IFN-gamma 的释放 [1]。
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	Pending
靶点	Lewis Y

储存&溶解度

存储

MB-311