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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FAM193B Polyclonal Antibody

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货号 TMAB-05849

Anti-FAM193B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FAM193B。Anti-FAM193B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FAM193B Polyclonal Antibody

Anti-FAM193B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05849

Anti-FAM193B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FAM193B。Anti-FAM193B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-FAM193B Polyclonal Antibody is a Rabbit antibody targeting FAM193B. Anti-FAM193B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FAM193B is a 902 amino acid protein that exists as two alternatively spliced isoforms. The gene encoding FAM193B maps to human chromosome 5, which contains 181 million base pairs and encodes around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FAM193B
抗原种属
Human
基因名称
FAM193B
基因ID
54540
蛋白名称
Protein FAM193B
Uniprot ID
Q96PV7
功能
FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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