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Anti-BCAM Antibody (4Z464)
还可以产品编号 TMAY-00511
Anti-BCAM Antibody (4Z464) 是一种 Mouse 抗体，靶向 BCAM。Anti-BCAM Antibody (4Z464) 可用于 ELISA(Cap)。
Anti-BCAM Antibody (4Z464)
Anti-BCAM Antibody (4Z464)
还可以产品编号 TMAY-00511
Anti-BCAM Antibody (4Z464) 是一种 Mouse 抗体，靶向 BCAM。Anti-BCAM Antibody (4Z464) 可用于 ELISA(Cap)。
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产品介绍
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抗原信息
| 产品描述 | Anti-BCAM Antibody (4Z464) is a Mouse antibody targeting BCAM. Anti-BCAM Antibody (4Z464) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4Z464 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The Lutheran (Lu) blood group and basal cell adhesion molecule (BCAM) antigens are both carried by 2 glycoprotein isoforms of the immunoglobulin superfamily representing receptors for the laminin alpha(5) chain. It is a transmembrane receptor with five immunoglobulin-like domains in its extracellular region, and is therefore classified as a member of the immunoglobulin (Ig) gene family. In addition to red blood cells, Lu/BCAM proteins are expressed in endothelial cells of vascular capillaries and in epithelial cells of several tissues. BCAM/LU has a wide tissue distribution with a predominant expression in the basal layer of the epithelium and the endothelium of blood vessel walls. As designated as CD239 recently, BCAM and LU share a significant sequence similarity with the CD146 (MUC18) and CD166, and themselves are adhesion molecules that bind laminin with high affinity. Laminins are found in all basement membranes and are involved in cell differentiation, adhesion, migration, and proliferation. BCAM is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. In addition, BCAM interacts with integrin in sickle red cells, and thus may potentially play a role in vaso-occlusive episodes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human BCAM Protein (TMPY-02637) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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