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Anti-PDGFRB Antibody-FITC (7C914)
还可以产品编号 TMAY-00931F
Anti-PDGFRB Antibody-FITC (7C914) 是一种 FITC-conjugated Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody-FITC (7C914) 可用于 FCM。
Anti-PDGFRB Antibody-FITC (7C914)
Anti-PDGFRB Antibody-FITC (7C914)
还可以产品编号 TMAY-00931F
Anti-PDGFRB Antibody-FITC (7C914) 是一种 FITC-conjugated Rabbit 抗体，靶向 PDGFRB。Anti-PDGFRB Antibody-FITC (7C914) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-PDGFRB Antibody-FITC (7C914) is a FITC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (7C914) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7C914 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human PDGFRβ (CD140b) expression on MG63 cells. Cells were stained with FITC-conjugated anti-Human PDGFRβ (CD140b). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PDGFRB / CD140b (rh PDGFRB / CD140b; TMPY-01207; NP_002600.1; Met1-Lys531) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human PDGFRB / CD140b Protein (TMPY-01207) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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