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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HEXDC Polyclonal Antibody

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货号 TMAB-06998

Anti-HEXDC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HEXDC。Anti-HEXDC Polyclonal Antibody 可用于 WB。

Anti-HEXDC Polyclonal Antibody

Anti-HEXDC Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06998

Anti-HEXDC Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HEXDC。Anti-HEXDC Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HEXDC Polyclonal Antibody is a Rabbit antibody targeting HEXDC. Anti-HEXDC Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic and Nuclear
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HEXDC
抗原种属
Human
基因名称
HEXD
基因ID
284004
蛋白名称
Hexosaminidase D
Uniprot ID
Q8WVB3
功能
Has hexosaminidase activity.
化学信息
分子量Theoretical: 54 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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