购物车
- 全部删除
您的购物车当前为空
Anti-ICOS ligand Antibody-PE (1W488)
还可以产品编号 TMAY-01901P
Anti-ICOS ligand Antibody-PE (1W488) 是一种 PE-conjugated Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody-PE (1W488) 可用于 FCM。
Anti-ICOS ligand Antibody-PE (1W488)
Anti-ICOS ligand Antibody-PE (1W488)
还可以产品编号 TMAY-01901P
Anti-ICOS ligand Antibody-PE (1W488) 是一种 PE-conjugated Mouse 抗体，靶向 ICOS ligand。Anti-ICOS ligand Antibody-PE (1W488) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-ICOS ligand Antibody-PE (1W488) is a PE-conjugated Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody-PE (1W488) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1W488 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of ICOSLG(CD275) expression on RPMI8226 cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICOS Ligand / B7-H2 (rh ICOS Ligand / B7-H2; TMPY-01672; NP_056074.1; Met1-Ser258) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. The present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production, and germinal center formation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human ICOS Ligand / B7-H2 protein (TMPY-01672) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-ICOS ligand Antibody-PE (1W488) | purchase Anti-ICOS ligand Antibody-PE (1W488) | Anti-ICOS ligand Antibody-PE (1W488) cost | order Anti-ICOS ligand Antibody-PE (1W488)
嗨！有任何问题？点我咨询
评论内容