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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BACE1 Antibody (5V275)

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货号 TMAB-03004

Anti-BACE1 Antibody (5V275) 是一种 Rabbit 抗体，靶向 BACE1。Anti-BACE1 Antibody (5V275) 可用于 WB。

Anti-BACE1 Antibody (5V275)

Anti-BACE1 Antibody (5V275)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03004

Anti-BACE1 Antibody (5V275) 是一种 Rabbit 抗体，靶向 BACE1。Anti-BACE1 Antibody (5V275) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-BACE1 Antibody (5V275) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (5V275) can be used in WB.
Ig Type
IgG
克隆号
5V275
反应种属
Mouse,Rat (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
浓度1mg/ml
研究背景Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
抗原信息
免疫原
A synthesized peptide: human BACE1
抗原种属
Human
基因名称
BACE1
基因ID
23621
蛋白名称
beta-secretase 1
Uniprot ID
P56817
功能
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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