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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NFIL3 Polyclonal Antibody

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货号 TMAB-09432

Anti-NFIL3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NFIL3。Anti-NFIL3 Polyclonal Antibody 可用于 WB。

Anti-NFIL3 Polyclonal Antibody

Anti-NFIL3 Polyclonal Antibody

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货号 TMAB-09432

Anti-NFIL3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NFIL3。Anti-NFIL3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NFIL3 Polyclonal Antibody is a Rabbit antibody targeting NFIL3. Anti-NFIL3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in bladder stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and muscle.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).[supplied by OMIM, Feb 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: human NFIL3
抗原种属
Human
基因名称
NFIL3
基因ID
4783
蛋白名称
Nuclear factor interleukin-3-regulated protein
Uniprot ID
Q16649
功能
Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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