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Anti-KIR2DL1 Antibody-PerCP (4W251)
还可以产品编号 TMAY-02503C
Anti-KIR2DL1 Antibody-PerCP (4W251) 是一种 PerCP-conjugated Rabbit 抗体，靶向 KIR2DL1。Anti-KIR2DL1 Antibody-PerCP (4W251) 可用于 FCM。
Anti-KIR2DL1 Antibody-PerCP (4W251)
Anti-KIR2DL1 Antibody-PerCP (4W251)
还可以产品编号 TMAY-02503C
Anti-KIR2DL1 Antibody-PerCP (4W251) 是一种 PerCP-conjugated Rabbit 抗体，靶向 KIR2DL1。Anti-KIR2DL1 Antibody-PerCP (4W251) 可用于 FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-KIR2DL1 Antibody-PerCP (4W251) is a PerCP-conjugated Rabbit antibody targeting KIR2DL1. Anti-KIR2DL1 Antibody-PerCP (4W251) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4W251 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human KIR2DL1(CD158a) expression on human whole blood lymphocytes. Human whole blood lymphocytes were stained with PerCP-conjugated anti-Human KIR2DL1(CD158a). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human KIR2DL1 / CD158a (rh KIR2DL1 / CD158a; TMPY-02629; NP_055033.2; Met1-His245) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Killer cell immunoglobulin-like receptor 2DL1 or KIR2DL1 is an inhibitory Natural Killer cell immunoglobulin-like receptor with two extracellular immunoglobulin domains. KIR2DL1 is a member of the Killer cell immunoglobulin-like receptor family whose members are classified by the number of the extracellular immunoglobulin domains and the length of the cytoplasm domain. KIR2DL1 is a transmembrane glycoprotein expressed by natural killer cells and subsets of T cells. KIR2DL1 down-regulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. It has been reported that the KIR2DL1 is bound to its class I MHC ligand, HLA-Cw4. The KIR2DL1-HLA-Cw4 interface exhibits charge and shape complementarity. Specificity is mediated by a pocket in KIR2DL1 that hosts the Lys80 residue of HLA-Cw4. Many residues conserved in HLA-C and KIR2DL receptors make different interactions in KIR2DL1-HLA-Cw4 and a previously reported KIR2DL2-HLA-Cw3 complex. A dimeric aggregate of KIR-HLA-C complexes was observed in one KIR2DL1-HLA-Cw4 crystal. |
| 偶联 | PerCP |
| 其他可选修饰符 | Unconjugated/APC/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human KIR2DL1 / CD158a protein (TMPY-02629) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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