Anti-BID Antibody (6V154)

Name: Anti-BID Antibody (6V154)
Brand: TargetMol
SKU: TMAY-00870
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAY-00870

别名 BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik

Anti-BID Antibody (6V154) 是一种 Rabbit 抗体，靶向 BID。Anti-BID Antibody (6V154) 可用于 WB,ELISA,IP。

Anti-BID Antibody (6V154)

还可以

产品编号 TMAY-00870 别名 BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik

Anti-BID Antibody (6V154) 是一种 Rabbit 抗体，靶向 BID。Anti-BID Antibody (6V154) 可用于 WB,ELISA,IP。

规格	价格	库存	数量
100 μL	¥ 2,284	5日内发货

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

联系我们获取更多批次信息

资源下载

产品操作手册

产品介绍

生物活性

产品描述	Anti-BID Antibody (6V154) is a Rabbit antibody targeting BID. Anti-BID Antibody (6V154) can be used in WB,ELISA,IP.
别名	BH3 interacting domain death agonist, AU022477, AI875481, 2700049M22Rik
Ig Type	Rabbit IgG
克隆号	6V154
交叉反应	Human
验证活性	1. BID was immunoprecipitated using: -Lane A:0.5 mg Jurkat Whole Cell Lysate. -Lane B:0.5 mg RAW264.7 Whole Cell Lysate. -2 µL anti-BID rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. -Primary antibody: -Anti-BID rabbit polyclonal antibody, at 1:200 dilution. -Secondary antibody: -Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution. -Developed using the odyssey technique. -Performed under reducing conditions. -Predicted band size: 22 kDa. -Observed band size: 22 kDa. 2. Anti-BID rabbit monoclonal antibody at 1:500 dilution. -Lane A: Jurkat Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:22 kDa. -Observed band size:22 kDa
应用	WB,ELISA,IP
推荐剂量	WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 0.5-2 μL/mg of lysate
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Human BID (rh BID; TMPY-02027; P55957-1; Met1-Asp195).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is important to cell death mediated by these proteases and thus is the sentinel to protease-mediated death signals. Recent studies further indicate that Bid may be more than just a killer molecule, it could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint. BID is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent. BID is activated by Caspase 8 in response to Fas/TNF-R1 death receptor activation. Activated BID is translocated to mitochondria and induces cytochrome c release, which in turn activates downstream caspases. BID action has been proposed to involve the mitochondrial re-location of its truncated form, tBid, to facilitate the release of apoptogenic proteins like cytochrome c.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Protein: Human BID protein (TMPY-02027)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.