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Anti-IL-22RA1 Antibody (6H79)

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产品编号 TMAY-00736

Anti-IL-22RA1 Antibody (6H79) 是一种 Mouse 抗体,靶向 IL-22RA1。Anti-IL-22RA1 Antibody (6H79) 可用于 ELISA。

Anti-IL-22RA1 Antibody (6H79)

Anti-IL-22RA1 Antibody (6H79)

Rating icon 还可以
产品编号 TMAY-00736

Anti-IL-22RA1 Antibody (6H79) 是一种 Mouse 抗体,靶向 IL-22RA1。Anti-IL-22RA1 Antibody (6H79) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
6H79
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL22RA1 (rh IL22RA1; TMPY-07014; NP_067081.2; Met1-Thr228). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IL22RA1 Protein (TMPY-07014)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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