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Anti-IL-22RA1 Antibody (6H79)
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产品编号 TMAY-00736
别名 interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Anti-IL-22RA1 Antibody (6H79) 是一种 Mouse 抗体，靶向 IL-22RA1。Anti-IL-22RA1 Antibody (6H79) 可用于 ELISA。
Anti-IL-22RA1 Antibody (6H79)
331 Anti-IL-22RA1 Antibody (6H79)
还可以产品编号 TMAY-00736 别名 interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1
Anti-IL-22RA1 Antibody (6H79) 是一种 Mouse 抗体，靶向 IL-22RA1。Anti-IL-22RA1 Antibody (6H79) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,694 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-22RA1 Antibody (6H79) is a Mouse antibody targeting IL-22RA1. Anti-IL-22RA1 Antibody (6H79) can be used in ELISA. |
| 别名 | interleukin 22 receptor, α1, interleukin 22 receptor, alpha 1 |
| Ig Type | Mouse IgG1 |
| 克隆号 | 6H79 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL22RA1 (rh IL22RA1; TMPY-07014; NP_067081.2; Met1-Thr228). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IL-22R belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains and is expressed in the colon, liver, lung, pancreas, and kidney. IL-22R also can be expressed in keratinocytes of normal skin as well as in psoriatic skin lesions. Overexpression of IL-22R can be detected in synovial fluid cells from rheumatoid arthritis and spondyloarthropathy patients. IL-22R is a component of the receptor for IL20, IL22, and IL24. The component of IL-22R formed by IL22RA1 and IL10RB enables IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptors for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. IL-22R mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human IL22RA1 Protein (TMPY-07014) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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