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Anti-IL-6 Antibody (2H625)

货号 TMAB-07672 一键复制产品信息
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Anti-IL-6 Antibody (2H625) 是一种 Mouse 抗体,靶向 IL-6。Anti-IL-6 Antibody (2H625) 可用于 WB。

Anti-IL-6 Antibody (2H625)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07672

Anti-IL-6 Antibody (2H625) 是一种 Mouse 抗体,靶向 IL-6。Anti-IL-6 Antibody (2H625) 可用于 WB。

Anti-IL-6 Antibody (2H625)
规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-IL-6 Antibody (2H625) is a Mouse antibody targeting IL-6. Anti-IL-6 Antibody (2H625) can be used in WB.
Ig Type
IgG
克隆号
2H625
反应种属
Human
验证活性
THP-1 (H) cells were treated with or without TPA (80 nM) and LPS (100 ng/ml,6 h) and Brefeldin A (300 ng/ml,3 h), 25 μg total protein per lane of cell lysates (see on figure) probed with IL-6 monoclonal antibody, unconjugated (TMAB-07672) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Secreted.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].
抗原信息
免疫原
Recombinant Protein: human IL-6 protein
抗原种属
Human
基因名称
IL6
基因ID
蛋白名称
Interleukin-6
功能
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
化学信息
分子量Theoretical: 23 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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