Name: LGR-5 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00743
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 358

6-8日内发货

10 μg

¥ 573

6-8日内发货

20 μg

¥ 938

5日内发货

50 μg

¥ 1,830

5日内发货

100 μg

¥ 3,100

5日内发货

200 μg

¥ 5,620

5日内发货

500 μg

¥ 12,400

5日内发货

生物活性

产品描述	G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.
生物活性	Human LGR-5, hFc Tag captured on CM5 Chip via Protein A can bind Human R-Spondin 3, His Tag with an affinity constant of 0.59 nM as determined in SPR assay.
研究背景	G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	O75473-1
蛋白构建	Gly22-Pro543
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 5 mM DTT (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	LGR5, HG38, G-protein coupled receptor HG38, G-protein coupled receptor 67, G-protein coupled receptor 49, GPR67, GPR49
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	85 kDa (predicted). Due to glycosylation, the protein migrates to 110-120 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

LGR-5 Protein, Human, Recombinant (hFc)

LGR-5 Protein, Human, Recombinant (hFc)

产品介绍

计算器

剂量转换

引用文献

技术支持

关键词