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TLR3 Protein, Cynomolgus, Recombinant (His)

TLR3 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPK-00544
别名: TLR3, CD283, IIAE2

TLR3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.04 kDa and the accession number is A0A2K5WT39.

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TLR3 Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,100 5日内发货
500 μg ¥ 12,400 5日内发货
1 mg ¥ 20,700 5日内发货
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产品目录号及名称: TLR3 Protein, Cynomolgus, Recombinant (His) (TMPK-00544)
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产品描述 TLR3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.04 kDa and the accession number is A0A2K5WT39.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-His
蛋白编号 A0A2K5WT39
别名 TLR3, CD283, IIAE2
蛋白构建 Ser31-Glu711
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 78.04 kDa (predicted). Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.

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Keywords

TLR3 Protein, Cynomolgus, Recombinant (His) TLR3 TLR-3 IIAE-2 TLR 3 IIAE 2 CD-283 CD 283 CD283 IIAE2 recombinant recombinant-proteins proteins protein

 

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