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Anti-CREB3L4 Antibody (5F216) 是一种 Mouse 抗体,靶向 CREB3L4。Anti-CREB3L4 Antibody (5F216) 可用于 WB。
Anti-CREB3L4 Antibody (5F216) 是一种 Mouse 抗体,靶向 CREB3L4。Anti-CREB3L4 Antibody (5F216) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 |
| 产品描述 | Anti-CREB3L4 Antibody (5F216) is a Mouse antibody targeting CREB3L4. Anti-CREB3L4 Antibody (5F216) can be used in WB. |
| Ig Type | IgG1 |
| 克隆号 | 5F216 |
| 反应种属 | Human,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Nucleus. Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus and Endoplasmic reticulum membrane. Golgi apparatus membrane. May also be located in Golgi apparatus. |
| 组织特异性 | According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| 免疫原 | Recombinant Protein: human CREB3L4 between 1-300 amino acids |
| 抗原种属 | Human |
| 基因名称 | CREB3L4 |
| 基因ID | |
| 蛋白名称 | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
| 功能 | Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). |
| 分子量 | Theoretical: 21 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |