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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MBD2 Antibody (6R377)

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货号 TMAB-08641

Anti-MBD2 Antibody (6R377) 是一种 Rabbit 抗体，靶向 MBD2。Anti-MBD2 Antibody (6R377) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

Anti-MBD2 Antibody (6R377)

Anti-MBD2 Antibody (6R377)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08641

Anti-MBD2 Antibody (6R377) 是一种 Rabbit 抗体，靶向 MBD2。Anti-MBD2 Antibody (6R377) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MBD2 Antibody (6R377) is a Rabbit antibody targeting MBD2. Anti-MBD2 Antibody (6R377) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
克隆号
6R377
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFIPFCM
推荐剂量
WB: 1:1000-5000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Nuclear, in discrete foci. Detected at replication foci in late S phase.
组织特异性Highly expressed in brain, heart, kidney, stomach, testis and placenta.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain.
抗原信息
免疫原
A synthesized peptide: human MBD2
抗原种属
Human
基因名称
MBD2
基因ID
8932
蛋白名称
Methyl-CpG-binding domain protein 2
Uniprot ID
Q9UBB5
功能
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
化学信息
分子量Theoretical: 43 kDa. Actual: 29, 43 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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