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顶部生物活性储存和溶解信息计算器

Anti-LRP1 Antibody (9Z880)

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Anti-LRP1 Antibody (9Z880)
产品编号 TMAC-02421
别名 TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR

Anti-LRP1 Antibody (9Z880) 是一种 Rabbit 抗体，靶向 LRP1。Anti-LRP1 Antibody (9Z880) 可用于 WB,ICC/IF,IHC,IP,FCM。

Anti-LRP1 Antibody (9Z880)

Anti-LRP1 Antibody (9Z880)

Rating icon 还可以
Anti-LRP1 Antibody (9Z880)
产品编号 TMAC-02421 别名 TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR

Anti-LRP1 Antibody (9Z880) 是一种 Rabbit 抗体，靶向 LRP1。Anti-LRP1 Antibody (9Z880) 可用于 WB,ICC/IF,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-LRP1 Antibody (9Z880) is a Rabbit antibody targeting LRP1. Anti-LRP1 Antibody (9Z880) can be used in WB,ICC/IF,IHC,IP,FCM.
别名TGFBR5, LRP1A, LRP, KPA, IGFBP3R1, IGFBP-3R, IGFBP3R, DDH3, CD91, APR, APOER, A2MR
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of LRP1 on different lysates using anti-LRP1 antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse liver, Lane 2: Mouse brain Lane, Lane 3: Mouse lung, Lane 4: Human liver, Lane 5: HepG2, Lane 6: Human lung.
2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-LRP1 antibody. Counter stained with hematoxylin.
3. ICC staining LRP1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS..
4. ICC staining LRP1 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining LRP1 in HUVEC cells (green). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of Hela cells with LRP1 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
IHC
IP
FCM
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:10-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1, also designated LRP and ?-2-Macroglobulin receptor, is an endocytic receptor that mediates the uptake of at least 15 ligands, including ?-2-Macroglobulin and apoE. LRP1 is cleaved into a membrane subunit and an extracellular subunit, which remain non-covalently associated. Proper folding and trafficking of LRP1 is facilitated by the receptor-associated protein (RAP), a molecular chaperone. The uptake of all known ligands through LRP1 can be blocked by RAP, which induces a conformational change in the receptor that renders it unable to bind ligands. LRP1, which is expressed in brain, liver and lung, is also implicated in Alzheimer??s disease (AD), as the human LRP gene localizes to a potential AD locus on chromosome 12.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q07954
化学信息
分子量Theoretical: 85 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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