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Anti-RIG-I Polyclonal Antibody
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产品编号 TMAB-01619
Anti-RIG-I Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RIG-I。Anti-RIG-I Polyclonal Antibody 可用于 WB。
Anti-RIG-I Polyclonal Antibody
Anti-RIG-I Polyclonal Antibody
还可以产品编号 TMAB-01619
Anti-RIG-I Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RIG-I。Anti-RIG-I Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-RIG-I Polyclonal Antibody is a Rabbit antibody targeting RIG-I. Anti-RIG-I Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Dog,Pig,Cow) |
| 验证活性 | Sample: Raw264.7 (Mouse) Cell Lysate at 30 μg Primary: Anti-DDX58 (TMAB-01619) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 106 kDa Observed band size: 114 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Note=Colocalized with TRIM25 at cytoplasmic perinuclear bodies. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG1/DDX58) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG1/DDX58 activates the kinases TBK1 and IKKe through the adaptor protein IPS1. These kinases then phosphorylate the transcription factors IRF3 and IRF7 which are essential for the expression of type-I interferons. RIG1/DDX58 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. |
| 免疫原 | KLH conjugated synthetic peptide: human DDX58 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | DNA / RNA binding,RNA Processing,Antiviral Signaling |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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