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Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) 是一种 PerCP-conjugated Rabbit 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) 可用于 FCM。
Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) 是一种 PerCP-conjugated Rabbit 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) 可用于 FCM。
产品描述 | Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) is a PerCP-conjugated Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-PerCP (5P550) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5P550 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human TFRC(CD71) in U937 cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe760) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
偶联 | PerCP |
其他可选修饰符 | Unconjugated/APC/FITC/PE |
可提供抗体种类 | 5 |
免疫原 | Recombinant Human Transferrin Receptor / TFRC / CD71 protein (TMPY-01873) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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