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Anti-CD93/C1qR1 Antibody (7E255)

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产品编号 TMAY-03774

Anti-CD93/C1qR1 Antibody (7E255) 是一种 Rabbit 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (7E255) 可用于 FCM。

Anti-CD93/C1qR1 Antibody (7E255)

Anti-CD93/C1qR1 Antibody (7E255)

Rating icon 还可以
产品编号 TMAY-03774

Anti-CD93/C1qR1 Antibody (7E255) 是一种 Rabbit 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (7E255) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD93/C1qR1 Antibody (7E255) is a Rabbit antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (7E255) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
7E255
交叉反应
Rat
验证活性
Flow cytometric analysis of Rat CD93 expression on SD rat bone marrow cells. Cells were stained with purified anti-Rat CD93, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD93/C1qR (rR CD93/C1qR; TMPY-00306; Q9ET61; Met1-Lys571).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC
可提供抗体种类
2
抗原信息
免疫原
Recombinant Rat CD93/C1qR Protein (TMPY-00306)
抗原种属
Rat
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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