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Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody

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Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody
产品编号 TMAC-00539
别名 p-CAMKIV (Thr196, 200), p-CAMKIV (T196, 200), CAMKIV (p-Thr196, 200), CAMKIV (p-T196, 200)

Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CAMKIV (Thr196, 200)。Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 可用于 WB,IHC,IF。

Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody

Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody
产品编号 TMAC-00539 别名 p-CAMKIV (Thr196, 200), p-CAMKIV (T196, 200), CAMKIV (p-Thr196, 200), CAMKIV (p-T196, 200)

Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CAMKIV (Thr196, 200)。Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 可用于 WB,IHC,IF。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKIV (Thr196, 200). Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody can be used in WB,IHC,IF.
别名p-CAMKIV (Thr196, 200), p-CAMKIV (T196, 200), CAMKIV (p-Thr196, 200), CAMKIV (p-T196, 200)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemistry analysis of paraffin-embedded human brain, using CaMK4 (Phospho-Thr196/200) Antibody. The picture on the right is blocked with the phospho peptide.
2. Immunofluorescence analysis of HeLa cells, using CaMK4 (Phospho-Thr196/200) Antibody. The picture on the right is blocked with the phospho peptide.
3. Western blot analysis of extracts from K562 cells treated with H2O2 using Phospho-CaMK4 (Thr196/200) antibody TMAC-00539. The lane on the right is treated with the antigen-specific peptide.
应用
推荐剂量
WB: 1:500-2000; IHC: 1:100-300; IF: 1:200-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2).
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human CaMK4 around the phosphorylation site of Thr196/200
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 60 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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