- 全部删除
- 您的购物车当前为空
Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CAMKIV (Thr196, 200)。Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CAMKIV (Thr196, 200)。Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody 可用于 WB,IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKIV (Thr196, 200). Anti-Phospho-CAMKIV (Thr196, 200) Polyclonal Antibody can be used in WB,IHC,IF. |
别名 | p-CAMKIV (Thr196, 200), p-CAMKIV (T196, 200), CAMKIV (p-Thr196, 200), CAMKIV (p-T196, 200) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemistry analysis of paraffin-embedded human brain, using CaMK4 (Phospho-Thr196/200) Antibody. The picture on the right is blocked with the phospho peptide. 2. Immunofluorescence analysis of HeLa cells, using CaMK4 (Phospho-Thr196/200) Antibody. The picture on the right is blocked with the phospho peptide. 3. Western blot analysis of extracts from K562 cells treated with H2O2 using Phospho-CaMK4 (Thr196/200) antibody TMAC-00539. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:100-300; IF: 1:200-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation. In the thymus, regulates the CD4+/CD8+ double positive thymocytes selection threshold during T-cell ontogeny. In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2). |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human CaMK4 around the phosphorylation site of Thr196/200 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 60 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容