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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NTN3 Polyclonal Antibody

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货号 TMAB-09660

Anti-NTN3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NTN3。Anti-NTN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NTN3 Polyclonal Antibody

Anti-NTN3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09660

Anti-NTN3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NTN3。Anti-NTN3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-NTN3 Polyclonal Antibody is a Rabbit antibody targeting NTN3. Anti-NTN3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space; extracellular matrix.
组织特异性Spinal cord.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, rather than attracted, by the netrin gradient. Neogenin serves as the primary guidance receptor for netrin-3. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection. Neogenin serves as the primary guidance receptor for netrin-3. During peripheral nerve development, high netrin-3 expression has been detected in mesenchymal cells, sensory ganglia and muscles. In humans, the gene encoding for the netrin-3 protein is localized to chromosome 16p13.3.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NTN3/Netrin-3
抗原种属
Human
基因名称
NTN3
基因ID
4917
蛋白名称
Netrin-3
Uniprot ID
O00634
功能
Netrins control guidance of CNS commissural axons and peripheral motor axons.
化学信息
分子量Theoretical: 59 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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