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顶部生物活性储存和溶解信息计算器

Anti-KRT1 Antibody (8C677)

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产品编号 TMAC-01073

别名 Type-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1), Keratin, type II cytoskeletal 1, Hair alpha protein, Cytokeratin-1 (CK-1), 67 kDa cytokeratin

Anti-KRT1 Antibody (8C677) 是一种 Rabbit 抗体，靶向 KRT1。Anti-KRT1 Antibody (8C677) 可用于 IHC,WB。

Anti-KRT1 Antibody (8C677)

Anti-KRT1 Antibody (8C677)

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产品编号 TMAC-01073 别名 Type-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1), Keratin, type II cytoskeletal 1, Hair alpha protein, Cytokeratin-1 (CK-1), 67 kDa cytokeratin

Anti-KRT1 Antibody (8C677) 是一种 Rabbit 抗体，靶向 KRT1。Anti-KRT1 Antibody (8C677) 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-KRT1 Antibody (8C677) is a Rabbit antibody targeting KRT1. Anti-KRT1 Antibody (8C677) can be used in IHC,WB.
别名Type-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1), Keratin, type II cytoskeletal 1, Hair alpha protein, Cytokeratin-1 (CK-1), 67 kDa cytokeratin
Ig Type
IgG
克隆号
8C677
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Cytokeratin 1 on different lysates using anti-Cytokeratin 1 antibody at 1/1,000 dilution. Positive control: Lane 1: 293T, Lane 2: Hela.
2. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
应用IHCWB
推荐剂量
WB: 1:1000; IHC: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and they aid in the characterization of malignant tumors. Cytokeratin 1 is highly expressed in several malignancies including epithelioid hemangioendohtheliomas, angiosarcomas, schwannomas, epithelioid sarcomas and synodal sarcomas. The gene encoding human Cytokeratin 1 maps to chromosome 12q13.13. Mutations in the gene encoding human Cytokeratin 1 lead to abnormal filament associations and epidermolytic hyperkeratosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P04264
化学信息
分子量Theoretical: 72 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Type-II keratin Kb 1KRT 1Keratin1 (K1)Hairα proteinHair α proteinHair a proteinCytokeratin1 (CK1)67 kDa-cytokeratin

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