Name: Phoenixin-20 TFA
Brand: TargetMol
SKU: T80424
Price: 718 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 718

In stock

5 mg

¥ 1,580

In stock

10 mg

¥ 2,370

In stock

25 mg

¥ 3,990

In stock

50 mg

¥ 5,980

In stock

产品介绍

生物活性

产品描述	Phoenixin-20 TFA (PNX-20 TFA) is a neuropeptide with hormone-like effects that promotes neuronal mitochondrial biogenesis by regulating the CREB-PGC-1α pathway, making it applicable for neurodegenerative diseases. It stimulates the hypothalamic-pituitary-gonadal (HPG) axis to enhance reproductive processes and exhibits anxiolytic properties.
体外活性	Phoenixin-20 TFA（1,10,100nM）处理 ZFL 细胞，能上调其卵黄原蛋白亚型和雌激素受体（esr2a 和 2b）mRNA 的表达。[3]
体内活性	方法：Phoenixin-20 TFA（100 ng/g，腹腔注射，持续7天）处理七氟醚吸入诱导的POCD 模型大鼠，观察其保护作用。结果：Phoenixin-20 TFA通过激活PKA/CREB信号传导，改善了吸入七氟醚诱导的大鼠POCD。[2]
别名	PNX-20 TFA

化学信息

分子量	2181.45 (free base)
分子式	C₁₀₁H₁₅₃N₂₅O₂₉.xC₂HF₃O₂
Smiles	[H]N[C@@H](C)C(NCC(N[C@]([H])(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N2CCC[C@H]2C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@H](C(N[C@@H](CC(O)=O)C(N5CCC[C@H]5C(N[C@@H](CC6=CC=CC=C6)C(N)=O)=O)=O)=O)CO)=O)=O)C(C)C)=O)CCCCN)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCC(N)=O)=O)C(C)C)=O)[C@@H](C)CC)=O)=O.OC(C(F)(F)F)=O
Sequence	Ala-Gly-Ile-Val-Gln-Glu-Asp-Val-Gln-Pro-Pro-Gly-Leu-Lys-Val-Trp-Ser-Asp-Pro-Phe-NH2
Sequence Short	AGIVQEDVQPPGLKVWSDPF-NH2

储存&溶解度

存储	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: 100 mg/mL, Sonication is recommended.

体内实验配液计算器