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别名 F11 receptor
Anti-JAM-A Antibody-APC (5E755) 是一种 APC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-APC (5E755) 可用于 FCM。
Anti-JAM-A Antibody-APC (5E755) 是一种 APC-conjugated Mouse 抗体,靶向 JAM-A。Anti-JAM-A Antibody-APC (5E755) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 T | ¥ 885 | 5日内发货 | |
| 100 T | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-JAM-A Antibody-APC (5E755) is a APC-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-APC (5E755) can be used in FCM. |
| 别名 | F11 receptor |
| Ig Type | Mouse IgG1 |
| 克隆号 | 5E755 |
| 交叉反应 | Human |
| 特异性 | Human JAM-A/F11 Receptor |
| 验证活性 | Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 2 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A / F11R / CD321 (rh JAM-A / F11R / CD321; TMPY-01035; NP_058642.1; Met 1-Ala 242) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Protein: Human JAM-A / F11R / CD321 protein (TMPY-01035) |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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