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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-p53 BP3 Polyclonal Antibody

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货号 TMAB-09879

Anti-p53 BP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 p53 BP3。Anti-p53 BP3 Polyclonal Antibody 可用于 WB。

Anti-p53 BP3 Polyclonal Antibody

Anti-p53 BP3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09879

Anti-p53 BP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 p53 BP3。Anti-p53 BP3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-p53 BP3 Polyclonal Antibody is a Rabbit antibody targeting p53 BP3. Anti-p53 BP3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Nucleus > PML body. Localizes to discrete nuclear foci which partly overlap with PML nuclear bodies. Targeted to PML nuclear bodies upon DNA damage.
组织特异性Expressed at highest levels in testis and at lower levels in adrenal gland, bone marrow, brain, colon, heart, kidney, liver, muscle, ovary, pancreas, placenta, prostate, skeletal muscle, skin, small intestine, spleen, stomach, testis, thymus, thyroid and uterus. Expressed in the alveolar epithelium of the lung. Expression is commonly decreased in colon adenocarcinomas and lung cancers.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus. [provided by RefSeq, Sep 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human p53 BP3
抗原种属
Human
基因名称
TOPORS
基因ID
10210
蛋白名称
E3 ubiquitin-protein ligase Topors
Uniprot ID
Q9NS56
功能
Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation.
化学信息
分子量Theoretical: 119 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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