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Anti-RAD51 Antibody (4A386)
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产品编号 TMAC-03510
别名 recombination protein A, RecA, E. coli, homolog of, RecA like protein, RecA homolog E. coli, RECA, RAD51A, RAD51 S cerevisiae homolog, RAD51 homolog(RecA homolog, E. coli)(S. cerevisiae), RAD51 homolog S. cerevisiae, RAD51 homolog, Rad 51, HsT16930, HsRad51, HRAD51, homolog of S cerevisiae RAD51, Homolog of E coli RecA, HGNC:9817, E coli RecA homolog, DNA repair protein rhp51, DNA repair protein RAD51 homolog 1, BRCC5, BRCC 5, BRCA1/BRCA2 containing complex, subunit 5
Anti-RAD51 Antibody (4A386) 是一种 Rabbit 抗体，靶向 RAD51。Anti-RAD51 Antibody (4A386) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-RAD51 Antibody (4A386)
Anti-RAD51 Antibody (4A386)
还可以产品编号 TMAC-03510 别名 recombination protein A, RecA, E. coli, homolog of, RecA like protein, RecA homolog E. coli, RECA, RAD51A, RAD51 S cerevisiae homolog, RAD51 homolog(RecA homolog, E. coli)(S. cerevisiae), RAD51 homolog S. cerevisiae, RAD51 homolog, Rad 51, HsT16930, HsRad51, HRAD51, homolog of S cerevisiae RAD51, Homolog of E coli RecA, HGNC:9817, E coli RecA homolog, DNA repair protein rhp51, DNA repair protein RAD51 homolog 1, BRCC5, BRCC 5, BRCA1/BRCA2 containing complex, subunit 5
Anti-RAD51 Antibody (4A386) 是一种 Rabbit 抗体，靶向 RAD51。Anti-RAD51 Antibody (4A386) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-RAD51 Antibody (4A386) is a Rabbit antibody targeting RAD51. Anti-RAD51 Antibody (4A386) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | recombination protein A, RecA, E. coli, homolog of, RecA like protein, RecA homolog E. coli, RECA, RAD51A, RAD51 S cerevisiae homolog, RAD51 homolog(RecA homolog, E. coli)(S. cerevisiae), RAD51 homolog S. cerevisiae, RAD51 homolog, Rad 51, HsT16930, HsRad51, HRAD51, homolog of S cerevisiae RAD51, Homolog of E coli RecA, HGNC:9817, E coli RecA homolog, DNA repair protein rhp51, DNA repair protein RAD51 homolog 1, BRCC5, BRCC 5, BRCA1/BRCA2 containing complex, subunit 5 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Rad51 on mouse testie tissue lytase using anti-Rad51 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-Rad51 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-Rad51 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Rad51 antibody. Counter stained with hematoxylin. 5. ICC staining Rad51 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining Rad51 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining Rad51 in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of Jurkat cells with Rad51 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| 应用 | |
| 推荐剂量 | WB: 1:500; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. Rad52 can interact with Rad51. Rad54A of the DEAD-like helicase superfamily binds to double-strand DNA and induces a DNA topological change, which is thought to facilitate homologous DNA pairing and stimulate DNA recombination. Rad54B of the DEAD-like helicase superfamily binds to double-stranded DNA and displays ATPase activity in the presence of DNA. Rad54B is abundant in testis and spleen, and mutations of this gene occur in primary lymphoma and colon cancer. MRE11 (meiotic recombination 11, ATLD, HNGS1) is a nuclear 3??-5?? exonuclease/endonuclease that associates with Rad50 and influences homologous recombination, telomere length maintenance, and DNA double-strand break repair. MRE11 is most abundant in proliferating tissues. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 37 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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