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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ATG5/APG5L Polyclonal Antibody

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货号 TMAB-02926

Anti-ATG5/APG5L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ATG5/APG5L。Anti-ATG5/APG5L Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ATG5/APG5L Polyclonal Antibody

Anti-ATG5/APG5L Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02926

Anti-ATG5/APG5L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ATG5/APG5L。Anti-ATG5/APG5L Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-ATG5/APG5L Polyclonal Antibody is a Rabbit antibody targeting ATG5/APG5L. Anti-ATG5/APG5L Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Note=Colocalizes with nonmuscle actin.
组织特异性Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In yeast, autophagy is an essential process for survival during nutrient starvation and cell differentiation. The process of autophagy is characterized as a non-selective degradation of cytoplasmic proteins into membrane stuctures called autophagosomes, and it is dependent on several proteins, including the autophagy proteins APG5 and APG7. Yeast Apg7 and the human homolog, APG7, share similarities with the ubiquitin-activating enzyme E1 in Saccharomyces cerevisiae and are likewise responsible for enzymatically activating the autophagy conjugation system. Apg5 and the human homolog, APG5 (also designated apoptosis-specific protein or APS), function as substrates for the autophagy protein Apg12. These proteins are covalently bonded together to form Apg12/APG5 conjugates, which are required for the progression of autophagy.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ATG5/APG5L
抗原种属
Human
基因名称
ATG5
基因ID
9474
蛋白名称
Autophagy protein 5
Uniprot ID
Q9H1Y0
功能
Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity).
May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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