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Anti-HSD3B7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HSD3B7。Anti-HSD3B7 Polyclonal Antibody 可用于 WB,ELISA。
Anti-HSD3B7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HSD3B7。Anti-HSD3B7 Polyclonal Antibody 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
| 产品描述 | Anti-HSD3B7 Polyclonal Antibody is a Rabbit antibody targeting HSD3B7. Anti-HSD3B7 Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse) |
| 应用 | WBELISA |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| 组织特异性 | High levels in liver and lung, moderate levels in spleen, brain, heart, kidney, jejunum and testis. Up-regulated in 3Y1 cells upon growth arrest. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human HSD3B7 |
| 抗原种属 | Human |
| 基因名称 | HSD3B7 |
| 基因ID | |
| 蛋白名称 | 3 beta-hydroxysteroid dehydrogenase type 7 |
| Uniprot ID | |
| 功能 | The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis. |
| 分子量 | Theoretical: 41 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |