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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RYK Antibody (6M535)

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货号 TMAB-12440

Anti-RYK Antibody (6M535) 是一种 Mouse 抗体，靶向 RYK。Anti-RYK Antibody (6M535) 可用于 WB。

Anti-RYK Antibody (6M535)

Anti-RYK Antibody (6M535)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12440

Anti-RYK Antibody (6M535) 是一种 Mouse 抗体，靶向 RYK。Anti-RYK Antibody (6M535) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

生物活性
产品描述
Anti-RYK Antibody (6M535) is a Mouse antibody targeting RYK. Anti-RYK Antibody (6M535) can be used in WB.
Ig Type
IgG2b,k
克隆号
6M535
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
组织特异性Observed in all the tissues examined.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
抗原信息
免疫原
Recombinant Protein: human RYK
抗原种属
Human
基因名称
RYK
基因ID
6259
蛋白名称
receptor like tyrosine kinase
Uniprot ID
P34925
功能
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
化学信息
分子量Theoretical: 68 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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