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IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

产品编号 TMPJ-00284
别名: Interleukin-7 receptor subunit alpha, IL-7R subunit α, IL-7R subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, Il7r, CD127, IL-7R-α, Interleukin-7 receptor subunit α, IL-7RA, IL-7 receptor subunit α

Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.

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IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 740 5日内发货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
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产品目录号及名称: IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) (TMPJ-00284)
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生物活性
技术参数
产品性质
生物活性 Loaded Human IL-7-His on HIS1K Biosensor, can bind Mouse IL-7RA-Fc with an affinity constant of 5.91 nM as determined in BLI assay. (Regularly tested)
产品描述 Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 61-75 KDa and the accession number is P16872.
种属 Mouse
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 P16872
别名 Interleukin-7 receptor subunit alpha, IL-7R subunit α, IL-7R subunit alpha, IL-7R-alpha, IL-7 receptor subunit alpha, Il7r, CD127, IL-7R-α, Interleukin-7 receptor subunit α, IL-7RA, IL-7 receptor subunit α
氨基酸序列 Glu21-Asp239
蛋白构建 Glu21-Asp239
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 61-75 KDa, reducing conditions
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 10% Sucrose, 3% Glycine, 100 mM NaCl, 0.1 mM EDTA, 0.05% Tween 80, pH 8.0.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses.

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Keywords

IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) Interleukin-7 receptor subunit alpha IL-7R subunit α IL-7R subunit alpha IL-7R-alpha IL-7 receptor subunit alpha Il7r CD127 IL-7R-α Interleukin-7 receptor subunit α IL-7RA IL-7 receptor subunit α CD 127 CD-127 recombinant recombinant-proteins proteins protein

 

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