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Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HER3/ERBB3 (Tyr1222)。Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-HER3/ERBB3 (Tyr1222)。Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody 可用于 WB,IHC-P,ICC/IF,ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER3/ERBB3 (Tyr1222). Anti-Phospho-HER3/ERBB3 (Tyr1222) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
别名 | p-HER3/ERBB3 (Y1222), p-HER3/ERBB3 (Tyr1222), HER3/ERBB3 (p-Y1222), HER3/ERBB3 (p-Tyr1222) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:20000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | erb-b2 receptor tyrosine kinase 3(ERBB3) Homo sapiens This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the m |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human HER3 around the phosphorylation site of Tyr1222. AA range:1191-1240 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 148 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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