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Anti-ABCA1 Polyclonal Antibody

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产品编号 TMAB-00019

别名 TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1

Anti-ABCA1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCA1。Anti-ABCA1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-ABCA1 Polyclonal Antibody

Anti-ABCA1 Polyclonal Antibody

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产品编号 TMAB-00019 别名 TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1

Anti-ABCA1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCA1。Anti-ABCA1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-ABCA1 Polyclonal Antibody is a Rabbit antibody targeting ABCA1. Anti-ABCA1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名TGD, TD, MGC165011, MGC164864, Membrane bound, HDLDT1, FLJ14958, Cholesterol Efflux Regulatory Protein, CERP, ATP-binding Cassette 1, ATP binding cassette transporter A1, ATP binding Cassette Transporter 1, ATP binding cassette sub family A member 1, ATP binding cassette sub family A ABC1 member 1, ATP binding Cassette 1, ABCA1, ABCA 1, ABC1, ABC Transporter 1, ABC 1
交叉反应
Human (predicted:Mouse,Rat,Pig,Cow,Horse)
验证活性
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (ABCA1) Polyclonal Antibody, Unconjugated (TMAB-00019) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Widely expressed, but most abundant in macrophages.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019]
抗原信息
免疫原
KLH conjugated synthetic peptide: human ABCA1
抗原种属
Human
基因名称
ABCA1
基因ID
19
蛋白名称
phospholipid-transporting ATPase ABCA1
Uniprot ID
O95477
研究领域
Metabolism of lipids and lipoproteins,Lipoprotein metabolism,Cholesterol Metabolism,Cholesterol Metabolism,Lipid metabolism,Lipoprotein metabolism,Cancer,Heart disease,Astrocyte marker,Lipid metabolism
功能
cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
化学信息
分子量Theoretical: 254 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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