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Anti-CHRAC1 Polyclonal Antibody

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货号 TMAB-04314

Anti-CHRAC1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHRAC1。Anti-CHRAC1 Polyclonal Antibody 可用于 WB。

Anti-CHRAC1 Polyclonal Antibody

Anti-CHRAC1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04314

Anti-CHRAC1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHRAC1。Anti-CHRAC1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-CHRAC1 Polyclonal Antibody is a Rabbit antibody targeting CHRAC1. Anti-CHRAC1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Cow,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators (1). CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex),which increases the accessibility of nucleosomal DNA in an ATP-dependent manner (2). Unlike other known chromatin remodelling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing (3). This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array (4). In the presence of CHRAC, the nucleosomal ATPase ISWI catalyses several ATP-dependent transitions of chromatin structure (5).
抗原信息
免疫原
KLH conjugated synthetic peptide: human CHRAC1
抗原种属
Human
基因名称
CHRAC1
基因ID
蛋白名称
Chromatin accessibility complex protein 1
Uniprot ID
功能
Forms a complex with DNA polymerase epsilon subunit POLE3 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome remodeling activity of ISWI/SNF2H and ACF1.
化学信息
分子量Theoretical: 14 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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