Cinnamaldehyde (Standard) is the reference compound for quantitative analysis, quality control, and biochemical research. Cinnamaldehyde exhibits antipyretic and sedative activities, inhibits the invasive potential of MDA-MB-435S cancer cells through downregulation of miR-27a, induces reactive oxygen species, exerts vasodilatory and anticancer effects, and has potential as an adjuvant in combination therapy with chemotherapeutics such as 5-fluorouracil and oxaliplatin, while also inhibiting melanoma progression via suppression of VEGF and HIF-a-mediated angiogenesis.