- 全部删除
- 您的购物车当前为空
Anti-THAP1 Antibody (8N883) 是一种 Mouse 抗体,靶向 THAP1。Anti-THAP1 Antibody (8N883) 可用于 WB,ICC,FCM。
Anti-THAP1 Antibody (8N883) 是一种 Mouse 抗体,靶向 THAP1。Anti-THAP1 Antibody (8N883) 可用于 WB,ICC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,995 | 5日内发货 |
产品描述 | Anti-THAP1 Antibody (8N883) is a Mouse antibody targeting THAP1. Anti-THAP1 Antibody (8N883) can be used in WB,ICC,FCM. |
别名 | THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of THAP1 on human THAP1 recombinant protein using anti-THAP1 antibody at 1/1,000 dilution. 2. Western blot analysis of THAP1 on HEK293 (1) and THAP1-hIgGFc transfected HEK293 (2) cell lysate using anti-THAP1 antibody at 1/1,000 dilution. 3. ICC staining THAP1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Jurkat cells with THAP1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | THAP1 (THAP domain containing, apoptosis associated protein 1) is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAP-type zinc finger, a conserved DNA-binding domain. Interacting with PAR4, THAP1 functions as a pro-apoptotic protein that acts in a zinc-dependent manner and enhances the likelihood of both TNF- and serum withdrawal-induced apoptosis, possibly playing a role in promyelocytic leukemia. The gene encoding THAP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 25 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容