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Anti-THAP1 Antibody (8N883)

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Anti-THAP1 Antibody (8N883)
产品编号 TMAC-04027
别名 THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik

Anti-THAP1 Antibody (8N883) 是一种 Mouse 抗体,靶向 THAP1。Anti-THAP1 Antibody (8N883) 可用于 WB,ICC,FCM。

Anti-THAP1 Antibody (8N883)

Anti-THAP1 Antibody (8N883)

Rating icon 还可以
Anti-THAP1 Antibody (8N883)
产品编号 TMAC-04027 别名 THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik

Anti-THAP1 Antibody (8N883) 是一种 Mouse 抗体,靶向 THAP1。Anti-THAP1 Antibody (8N883) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-THAP1 Antibody (8N883) is a Mouse antibody targeting THAP1. Anti-THAP1 Antibody (8N883) can be used in WB,ICC,FCM.
别名THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik
交叉反应
Human
验证活性
1. Western blot analysis of THAP1 on human THAP1 recombinant protein using anti-THAP1 antibody at 1/1,000 dilution.
2. Western blot analysis of THAP1 on HEK293 (1) and THAP1-hIgGFc transfected HEK293 (2) cell lysate using anti-THAP1 antibody at 1/1,000 dilution.
3. ICC staining THAP1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Jurkat cells with THAP1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景THAP1 (THAP domain containing, apoptosis associated protein 1) is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAP-type zinc finger, a conserved DNA-binding domain. Interacting with PAR4, THAP1 functions as a pro-apoptotic protein that acts in a zinc-dependent manner and enhances the likelihood of both TNF- and serum withdrawal-induced apoptosis, possibly playing a role in promyelocytic leukemia. The gene encoding THAP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 25 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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